Research: The Hidden Link Between Circadian Entropy and Mental Health Disorders

LDS 9 CS circadian rhythm 400

September 21, 2022

The high overlapping nature of various features across multiple mental health disorders suggests the existence of common psychopathology factor(s) (p-factors) that mediate similar phenotypic presentations across distinct but relatable disorders. In this perspective, we argue that circadian rhythm disruption (CRD) is a common underlying p-factor that bridges across mental health disorders within their age and sex contexts. We present and analyze evidence from the literature for the critical roles circadian rhythmicity plays in regulating mental, emotional, and behavioral functions throughout the lifespan.

A review of the literature shows that coarse CRD, such as sleep disruption, is prevalent in all mental health disorders at the level of etiological and pathophysiological mechanisms and clinical phenotypical manifestations. Finally, we discuss the subtle interplay of CRD with sex in relation to these disorders across different stages of life. Our perspective highlights the need to shift investigations towards molecular levels, for instance, by using spatiotemporal circadian “omic” studies in animal models to identify the complex and causal relationships between CRD and mental health disorders.

Go HERE for the full paper

 

Related Articles


Changing Scene

  • Acquisition of Cree Lighting US

    September 20, 2023 The acquisitions solidify ADLT Lighting Group’s position as a global leader in the lighting industry and reinforce its commitment to innovation and excellence. The ADLT Lighting Group is thrilled to announce the successful acquisition of Cree Lighting US, E-conolight, and Cree Lighting Canada on September 8th, 2023, marking a significant milestone in the company’s… Read More…

  • BFC Lighting Solutions Partners with BJ Take Inc.

    September 19, 2023 Adapted from Linkedin Post BFC Lighting Solutions is delighted to be announcing their new partnership with, BJ Take Inc., a Canadian manufacturer that they are particularly proud of! BJ Take Inc. represents a significant asset that BFC Lighting Solutions proudly adds to their list of valuable partners. This Canadian company distinguishes itself… Read More…


Design

  • Architectural lighting brings industrial building to life as part of City of Montreal rejuvenation project

    September 11, 2023 Valeco Energie Québec Inc. is a renewable energy development company found on the edge of Frédérick-Back park in Montreal. Valeco acts as the operators of the Biomont Energy cogeneration plant in the Saint-Michel environmental complex, which recovers biogas from the former landfill site and transforms it into green energy. “The park used… Read More…

  • St-Denis Thompson with Eureka Lighting

    St-Denis Thompson with Eureka Lighting

    September 6, 2023 Industrial-era lighting design complements historic office architecture Montreal contractor St-Denis Thompson specializes in building restoration. So, it was no coincidence that it moved its head office to a historic 1908 building on the banks of the Lachine Canal. St-Denis Thompson hired local interior design firm Folio Design to create new offices with… Read More…


New Products

  • BS101LRE Retrofit Kit from Beluce

    BS101LRE Retrofit Kit from Beluce

    September 19, 2023 The BS101LRE is the economical retrofit kit for the BS111 and BS101 The BS101LRE Retrofit Kit allows you to upgrade your existing BS111 and BS101 from fluorescent to LED. To retrofit all you need to do is remove the existing lens and reflector holding the lamps & ballast from the existing fixture… Read More…

  • S4i Integrator Solutions for Seamless Control

    S4i Integrator Solutions for Seamless Control

    September 19, 2023 S4i IB Now Integrates with Crestron Electronics to provide Seamless Control of Casambi Technologies Lighting S4i Solutions for Integrators is pleased to announce that the their Integration Broker (IB) now integrates with Crestron (SIMPL) control systems. This integration allows users to seamlessly control Casambi lighting from their Crestron system. Casambi is a wireless lighting control system that uses Bluetooth Low Energy… Read More…